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Article

Evidence for major histocompatibility complex-mediated effects on spermatogenesis in humans.

Human reproduction (Oxford, England) - 1 Jan 2000

van der Ven K, Fimmers R, Engels G, van der Ven H, Krebs D

Abstract excerpt

Studies in fertile and infertile populations suggest an influence of genes of the major histocompatibility complex (MHC) on reproduction, although it remains unresolved if MHC-mediated effects on fertility are based on direct immunological or non-immunological effects of human leukocyte antigen (HLA) genes or rather on defects in MHC-associated non-HLA genes which affect gamete quality and embryonic development....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10611211
DOI: 10.1093/humrep/15.1.189

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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