Article
Is HLA-E a possible genetic marker relevant for natural conception?
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Dec 2016
Gelmini Georgia Fernanda, Costa Cynthia Hernandes, Nardi Fabiola da Silva, Wowk Pryscilla Fanini, Mattar Sibelle Botogosque, Schuffner Alessandro, Bicalho Maria da Graça, Roxo Valéria Maria Munhoz Sperandio
Abstract excerpt
BACKGROUND: HLA-E products, class Ib human leukocyte antigens, act in the immunology of human reproduction as modulators of the maternal immune system during pregnancy. AIMS: To evaluate HLA-E role in the establishment of a viable pregnancy. MATERIALS & METHODS: HLA-E was genotyped by sequence-based typing (SBT) and analyzed for specific polymorphisms, comparing couples who underwent assisted reproduction...
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