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Article

Disruption of clh-1, a chloride channel gene, results in a wider body of Caenorhabditis elegans.

Journal of molecular biology - 26 Nov 1999

Petalcorin M I, Oka T, Koga M, Ogura K, Wada Y, Ohshima Y, Futai M

Abstract excerpt

We cloned the clh-1 gene coding for a putative ClC chloride channel in Caenorhabditis elegans. The gene product exhibited a high degree of homology with human ClC-1 and ClC-2. The clh-1 gene was predominantly expressed in the hypodermis, including seam cells. Null mutations of clh-1 caused a significantly wider body and an abnormal alae structure. High osmolarity in the culture medium restored the normal body...

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Source

Identifiers

PMID: 10610763
DOI: 10.1006/jmbi.1999.3241

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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