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Article

Transmission-blocking immunity to <i>Plasmodium falciparum</i> in malaria-immune individuals is associated with antibodies to the gamete surface protein Pfs230

1 Nov 1999

Abstract excerpt

Malaria-immune human sera were tested for their ability to affect the infectivity of Plasmodium falciparum gametocytes to Anopheles stephensi mosquitoes. Transmission-reducing effects of the sera were associated with the presence of antibodies to the gamete surface protein, Pfs230. Enhancement of transmission, manifest as elevated numbers of oocysts relative to controls, was observed for a number of sera, but was...

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PMID: 10599074
DOI: 10.1017/s0031182099005041

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Related research

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Transmission-blocking immunity to <i>Plasmodium falciparum</i> in malaria-immune individuals is associated with antibodies to the gamete surface protein Pfs230PMID 10599074Read ↗

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