Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Complex patterns of intragenic polymorphism at the PDGFA locus.

Human genetics - 1 Nov 1999

Bonthron D T, Smith S J, Campbell R

Abstract excerpt

The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site. Here, we show that the PDGFA genes of four ape species and an Old-World monkey all have similar complex minisatellites at this position. Comparison of their structures...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 7
Share to DNA Primers
Share to Evolution, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hominidae

Share to Minisatellite Repeats

Share to Platelet-Derived Growth Factor

Share to Sequence Homology, Amino Acid

Share to Species Specificity

Source

Identifiers

PMID: 10598812
DOI: 10.1007/s004390051130

Genes

PDGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Complex patterns of intragenic polymorphism at the PDGFA locus.PMID 10598812Read ↗

PDGFRa mutations in humans with isolated cleft palate.Semantic proximity Read ↗

The structure and evolution of the human salivary proline-rich protein gene family.Semantic proximity Read ↗

DNA sequence variants of the platelet-derived growth factor A-chain gene.Semantic proximity Read ↗

Genetic polymorphism of apolipoprotein A-IV in the chimpanzee: common deletion of a conserved 12-nucleotide tandem repeat.Semantic proximity Read ↗

Disruption of the PDGFB gene in a 1;22 translocation patient does not cause Costello syndrome.Semantic proximity Read ↗

Novel human PDGFA gene transcripts derived by alternative mRNA splicing.Semantic proximity Read ↗

Structure, Organization, and Transcription Units of the Human α-Platelet-Derived Growth Factor Receptor Gene, PDGFRASemantic proximity Read ↗

Dinucleotide repeat polymorphism at the human PDGF RB gene.Semantic proximity Read ↗

Platelet-derived growth factor receptor alpha-subunit gene (Pdgfra) is deleted in the mouse patch (Ph) mutation.Semantic proximity Read ↗

MspI restriction fragment length polymorphism at the glycoprotein hormone alpha-subunit locus. Association of certain genotypes with neoplasia.Semantic proximity Read ↗

Allelic diversity at minisatellite MS205 (D16S309): evidence for polarized variability.Semantic proximity Read ↗

Molecular characterization of an intragenic minisatellite (VNTR) polymorphism in the human parathyroid hormone-related peptide gene in chromosome region 12p12.1-p11.2.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.