Article
Generalization of the extended transmission disequilibrium test to two unlinked disease loci.
Genetic epidemiology - 1 Jan 1999
Morris A, Whittaker J
Abstract excerpt
The extended transmission disequilibrium test (ETDT) of Sham and Curtis [1995] is a powerful test of the null hypothesis of no linkage between a multi-allelic marker locus and a disease susceptibility locus of unknown location in the presence of association between alleles at the two loci. We propose a generalization of the ETDT to test simultaneously for linkage of markers to two unlinked disease loci. Analysis...
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