Linkage and association analyses of alcoholism using a regression-based transmission/disequilibrium test.

Abstract excerpt

Recently, George et al. proposed a regression-based transmission/disequilibrium test for linkage using information on the parent-to-offspring transmission status of an allele at a marker locus. We extended this test by simultaneously testing for any population association by incorporating the presence/absence status of the associated allele as a covariate in the model. We used this method to analyze markers on...

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