Fine mapping of a genetic locus for Peutz-Jeghers syndrome on chromosome 19p.

Article

Fine mapping of a genetic locus for Peutz-Jeghers syndrome on chromosome 19p.

Cancer research - 1 Sept 1997

Amos C I, Bali D, Thiel T J, Anderson J P, Gourley I, Frazier M L, Lynch P M, Luchtefeld M A, Young A, McGarrity T J, Seldin M F

Abstract excerpt

Peutz-Jeghers syndrome (PJS) was recently mapped in a single report to the telomeric region of chromosome 19p (A. Hemminki et al., Nat. Genet., 15: 87-90, 1997). Our studies confirm this location and provide further localization of the PJS locus. In the five families examined, there were no recom...

Topics

Chromosome Mapping
Chromosomes, Human, Pair 19
Female
Genetic Markers
Heterozygote
Humans
Lod Score
Male
Pedigree
Peutz-Jeghers Syndrome
Phenotype

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.