Article
Neuronal loss and beta-amyloid removal in the amygdala of people with Down syndrome.
Neurobiology of aging - 1 Jan 2000
Weģiel J, Wísniewski H M, Moryś J, Tarnawski M, Kuchna I, Dziewiatkowski J, Pirttilä T, Krivimäki T, Lehtimäki T, Lach B
Abstract excerpt
The decrease in the number of neurons free of neurofibrillary changes, neurons with neurofibrillary degeneration, and the total volume of beta-amyloid (A beta) deposits in the amygdala of people with Down syndrome and in late stages of Alzheimer disease were estimated by using morphometry and regression analysis. This model predicts that the duration of neurofibrillary changes from the pretangle stage to ghost...
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