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Article

Polysaccharide vaccines as probes of antibody repertoires in man

1 Oct 1999

Abstract excerpt

Antibodies specific for capsular polysaccharide epitopes mediate immunity to encapsulated bacterial pathogens, and accordingly, vaccine development has focused upon the induction of these specificities. Efficacious vaccines, consisting of either polysaccharide alone or polysaccharide coupled to protein carriers, have been developed for a number of pathogens. Their clinical importance notwithstanding, these...

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PMID: 10582166
DOI: 10.1111/j.1600-065x.1999.tb01343.x

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