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Article

Structure of a protective epitope of group B Streptococcus type III capsular polysaccharide

24 Apr 2017

Abstract excerpt

(GBS) disease with the introduction of intrapartum antibiotic prophylaxis, this pathogen remains a leading cause of neonatal infection. Capsular polysaccharide conjugate vaccines have been tested in phase I/II clinical studies, showing promise for further development. Mapping of epitopes recognized by protective antibodies is crucial for understanding the mechanism of action of vaccines and for enabling antigen...

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PMID: 28439022
DOI: 10.1073/pnas.1701885114

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