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Article

Anti-HIV effect of saquinavir combined with ritonavir is limited by previous long-term therapy with protease inhibitors.

AIDS research and human retroviruses - 20 Nov 1999

Gatanaga H, Aizawa S, Kikuchi Y, Tachikawa N, Genka I, Yoshizawa S, Yamamoto Y, Yasuoka A, Oka S

Abstract excerpt

Combination therapy of saquinavir (SQV) and ritonavir (RTV) seems to have a strong antiretroviral effect pharmacokinetically. The purpose of this study was to examine the effectiveness of combined therapy using SQV and RTV in patients previously treated with protease inhibitors (PIs) and to identify the factors compromising the response to such combination therapy. Nineteen HIV-infected Japanese patients...

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Source

Identifiers

PMID: 10580399
DOI: 10.1089/088922299309775

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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