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Article

Protein isoaspartyl methyltransferase protects from Bax-induced apoptosis.

Gene - 29 Nov 1999

Huebscher K J, Lee J, Rovelli G, Ludin B, Matus A, Stauffer D, Fürst P

Abstract excerpt

Protein L-isoaspartyl methyltransferase (Pimt) is a highly conserved enzyme utilising S-adenosylmethionine (AdoMet) to methylate aspartate residues of proteins damaged by age-related isomerisation and deamidation. We have been particularly interested in this enzyme since addition of the compound CGP3466 to primary rat astroglia cell cultures resulted in an upregulation of Pimt at the mRNA level, as shown here by...

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Identifiers

PMID: 10580153
DOI: 10.1016/s0378-1119(99)00443-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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