Article
Evidence for the segregation of a major gene for human plasma GABA levels.
Molecular psychiatry - 1 Nov 1999
Petty F, Fulton M, Kramer G L, Kram M, Davis L L, Rush A J
Abstract excerpt
Gamma-aminobutryic acid (GABA) is a major neurotransmitter in the central nervous system, and plasma levels of GABA may reflect brain GABA activity. In 35-40% of patients with mood disorders, plasma GABA levels are low compared to psychiatrically normal controls. Low plasma GABA in this subgroup of patients has characteristics of a biological trait marker for mood disorders. Low plasma GABA is also found in a...
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