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Article

Two mutations identified in the androgen receptor of the new human prostate cancer cell line MDA PCa 2a.

The Journal of urology - 1 Dec 1999

Zhao X Y, Boyle B, Krishnan A V, Navone N M, Peehl D M, Feldman D

Abstract excerpt

PURPOSE: We have characterized the androgen receptor (AR) in a new human prostate cancer cell line, MDA PCa 2a, that has recently been established from a bone metastasis of a patient whose cancer exhibited androgen-independent growth. MATERIALS AND METHODS: Androgen responsiveness of these cells was assessed by measuring the effect of DHT and R1881 on cell growth and PSA secretion. Scatchard analysis was used to...

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Identifiers

PMID: 10569618
DOI: 10.1016/S0022-5347(05)68158-X

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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