Article
Associations of MHC genes with levels of caries-inducing organisms and caries severity in African-American women.
Human immunology - 1 Oct 1999
Acton R T, Dasanayake A P, Harrison R A, Li Y, Roseman J M, Go R C, Wiener H, Caufield P W
Abstract excerpt
The aim of this investigation was to evaluate the relationship between MHC alleles at the HLA-DRB1, DQB1 and TNFa microsatellite loci and levels of oral bacteria that play a role in the etiology of dental caries, and the DMFS index in 186 AA primparous women. The average age of the cohort was 20.8+/-3.7 years. The median DMFS index was 9 (range 0-68). High levels of S. mutans were positively associated with...
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