Article
Host and microbiological factors related to dental caries development.
Caries research - 1 Jan 2008
De Soet J J, van Gemert-Schriks M C M, Laine M L, van Amerongen W E, Morré S A, van Winkelhoff A J
Abstract excerpt
Studies on dental caries suggest that in severe cases it may induce a systemic immune response. This occurs particularly when caries progresses into pulpal inflammation and results in abscess or fistula formation (AFF). We hypothesized that severe dental caries will affect the general health of children. The acute phase proteins alpha-1-acid glycoprotein (AGP), C-reactive protein (CRP) and the cytokine neopterin...
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