Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lysosomal high molecular weight multienzyme complex.

Cellular & molecular biology letters - 1 Jan 2003

Ostrowska Halina, Krukowska Katarzyna, Kalinowska Joanna, Orłowska Mirosława, Lengiewicz Ilona

Abstract excerpt

Three acidic glycosidases: beta-galactosidase (beta-GAL, EC 3.2.1.23), alpha-neuraminidase (NEUR, sialidase, EC 3.2.1.18), N-acetylaminogalacto-6-sulfate sulfatase (GALNS, EC 3.1.6.4) and serine carboxypepidase cathepsin A (EC 3.4.16.1) form a functional high molecular weight complex in the lysosomes. The major constituent of this complex is cathepsin A, the so-called "lysosomal protective protein" (PPCA). By...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Molecular Weight
Share to Lysosomes
Share to beta-Galactosidase

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cathepsin A

Share to Lysosomal Storage Diseases

Share to Multienzyme Complexes

Share to Mutation

Share to Neuraminidase

Source

Identifiers

PMID: 12655352

Genes

GAL
GALNS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lysosomal high molecular weight multienzyme complex.PMID 12655352Read ↗

Cathepsin A/protective protein: an unusual lysosomal multifunctional protein.Semantic proximity Read ↗

The atomic model of the human protective protein/cathepsin A suggests a structural basis for galactosialidosis.Semantic proximity Read ↗

Disorders of glycoprotein degradation.Semantic proximity Read ↗

Inherited diseases caused by mutations in cathepsin protease genes.Semantic proximity Read ↗

Cathepsins in the Pathophysiology of Mucopolysaccharidoses: New Perspectives for Therapy.Semantic proximity Read ↗

Molecular basis of GM1 gangliosidosis and Morquio disease, type B. Structure-function studies of lysosomal beta-galactosidase and the non-lysosomal beta-galactosidase-like protein.Semantic proximity Read ↗

Glycoprotein lysosomal storage disorders: alpha- and beta-mannosidosis, fucosidosis and alpha-N-acetylgalactosaminidase deficiency.Semantic proximity Read ↗

Molecular pathology of galactosialidosis in a patient affected with two new frameshift mutations in the cathepsin A/protective protein gene.Semantic proximity Read ↗

Lysosomal alpha-mannosidase and alpha-mannosidosis.Semantic proximity Read ↗

Lysosomal multienzymatic complex-related diseases: a genetic study among Portuguese patients.Semantic proximity Read ↗

Structure-function relationship for lysosomal enzymes.Semantic proximity Read ↗

Lysosomal proteomics and disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.