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Article

Spire contains actin binding domains and is related to ascidian posterior end mark-5.

Development (Cambridge, England) - 1 Dec 1999

Wellington A, Emmons S, James B, Calley J, Grover M, Tolias P, Manseau L

Abstract excerpt

Spire is a maternal effect locus that affects both the dorsal-ventral and anterior-posterior axes of the Drosophila egg and embryo. It is required for localization of determinants within the developing oocyte to the posterior pole and to the dorsal anterior corner. During mid-oogenesis, spire mutants display premature microtubule-dependent cytoplasmic streaming, a phenotype that can be mimicked by pharmacological...

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Source

Identifiers

PMID: 10556052
DOI: 10.1242/dev.126.23.5267

Genes

CDC42
RAC1
RHOA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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