Article
Effect of all-trans-retinoic acid on c-fms proto-oncogene [colony-stimulating factor 1 (CSF-1) receptor] expression and CSF-1-induced invasion and anchorage-independent growth of human breast carcinoma cells.
Cancer research - 1 Nov 1999
Sapi E, Flick M B, Tartaro K, Kim S, Rakhlin Y, Rodov S, Kacinski B M
Abstract excerpt
Abnormal expression of c-fms proto-oncogene, which encodes for the macrophage colony-stimulating factor-1 (CSF-1) receptor, has been observed in a variety of carcinomas of epithelial origin, including those of the breast. Here, we have investigated the effect of retinoic acid (RA), an important regulator of normal differentiation of mammary epithelial tissues, on the expression of the c-fms gene and CSF-1/CSF-1...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.