Article
Selective Promoter Usage of the Human Estrogen Receptor-α Gene and Its Regulation by Estrogen
1 Nov 1999
Abstract excerpt
Three promoters have been identified for the human estrogen receptor-alpha gene. The positions of promoters A and B are known whereas that of the recently identified promoter C is not. Cloning and hybridization experiments demonstrated that promoter C is located more than 21 kb upstream of promoter A. The use of the three promoters was examined in estrogen receptor-positive breast cancer cell lines, cell lines...
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