Article
DNA distortion as a factor in nucleosome positioning.
Journal of molecular biology - 29 Oct 1999
Fitzgerald D J, Anderson J N
Abstract excerpt
In a previous report we constructed a synthetic DNA sequence that directed the deposition of histone octamers to a single site, and it was proposed that DNA distortion was involved in the positioning effect. In the present study we utilized the chemical probe potassium permanganate to identify sites of DNA distortion in the synthetic positioning sequence. A permanganate hypersite was identified 15 bp from the...
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