Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Umbelliferone analogues and their potential to inhibit Benzo(a)pyrene- and hydrogen peroxide-induced mutations.

Journal of natural products - 1 Oct 1999

Pillai S P, Menon S R, Mitscher L A, Pillai C A, Shankel D M

Abstract excerpt

Following the natural product lead, farneciferol-D (kopetdaghin, 8), some ether analogues of umbelliferone were synthesized and assayed for their potential to be antimutagenic/anticarcinogenic against mutations induced by benzo(a)pyrene, a potent mutagen/carcinogen, and hydrogen peroxide, and for their ability to function as free radical scavengers. The "true" antimutagenic effect of these compounds was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimutagenic Agents
Share to Benzo(a)pyrene
Share to Free Radical Scavengers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hydrogen Peroxide

Share to Magnetic Resonance Spectroscopy

Share to Molecular Structure

Share to Salmonella typhimurium

Share to Superoxides

Source

Identifiers

PMID: 10543892
DOI: 10.1021/np990048u

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Umbelliferone analogues and their potential to inhibit Benzo(a)pyrene- and hydrogen peroxide-induced mutations.PMID 10543892Read ↗

Chemical and biological characterisation of Machaerium hirtum (Vell.) Stellfeld: absence of cytotoxicity and mutagenicity and possible chemopreventive potential.Semantic proximity Read ↗

Mutagenic activity of four furocoumarins: angelicin, 4,5'-dimethyl-angelicin, psoralen and 8-methyl-psoralen on V79 Chinese hamster cells.Semantic proximity Read ↗

The cytotoxic and mutagenic effects of 4CMB, BC and 4HMB in V79 Chinese hamster cells.Semantic proximity Read ↗

Antimutagenic and anticancer activity of Darjeeling tea in multiple test systems.Semantic proximity Read ↗

Safety evaluation of vitamin K2 (menaquinone-7) via toxicological tests.Semantic proximity Read ↗

Genotoxicity assessment of piperitenone oxide: An in vitro and in silico evaluation.Semantic proximity Read ↗

Comparative study of the antimutagenic properties of vitamins C and E against mutation induced by norfloxacin.Semantic proximity Read ↗

Review of the mutagenicity/genotoxicity of butylated hydroxytoluene.Semantic proximity Read ↗

Anthracene-9,10-diones as potential anticancer agents: bacterial mutation studies of amido-substituted derivatives reveal an unexpected lack of mutagenicity.Semantic proximity Read ↗

Safety assessment of a novel water-soluble extract of Boswellia serrata gum resin: acute toxicity, 90-day sub-chronic toxicity, Ames' bacterial reverse mutation, and in vivo micronucleus assays.Semantic proximity Read ↗

Inhibition of benzo[a]pyrene dihydrodiol epoxide mutagenicity by synthetic analogues of ellagic acid.Semantic proximity Read ↗

Genotoxic and Antigenotoxic Potential of Momordica charantia Linn (Cucurbitaceae) in the Wing Spot Test of Drosophila melanogaster.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.