Article
Functional characterisation of altered outer membrane proteins for tetracycline resistance in Escherichia coli.
International journal of antimicrobial agents - 1 Oct 2008
Zhang Dan-feng, Jiang Bin, Xiang Zhi-ming, Wang San-ying
Abstract excerpt
Alterations in the outer membrane (OM) proteome in response to tetracycline have been reported in Escherichia coli K-12, but information regarding their functional profile is not available. In this study, upregulation of FimD, Tsx, OmpW, OmpC and TolC and downregulation of LamB in response to tetracycline were detected and confirmed by two-dimensional gel electrophoresis subproteomics and Western blotting,...
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