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Article

Nuclear and Cytoplasmic Maturation of Mouse Oocytes After Treatment with Synthetic Meiosis-Activating Sterol In Vitro1

1 Nov 1999

Abstract excerpt

Synthetically produced meiosis-activating sterol, a sterol originally derived from follicular fluid (FF-MAS), induces meiotic maturation of mouse oocytes in vitro. We therefore compared FF-MAS-induced maturation of naked mouse oocytes arrested in prophase I by either hypoxanthine (Hx) or forskolin (Fo) with spontaneous maturation of naked oocytes. FF-MAS-treated oocytes overcame the meiotic block by Hx or Fo,...

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PMID: 10529286
DOI: 10.1095/biolreprod61.5.1362

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