Article
Genetic analysis of the contribution of IL10 to systemic lupus erythematosus.
The Journal of rheumatology - 1 Oct 1999
Alarcón-Riquelme M E, Lindqvist A K, Jonasson I, Johanneson B, Sandino S, Alcocer-Varela J, Granados J, Kristjánsdóttir H, Gröndal G, Svenungsson E, Lundberg I, Steinsson K, Klareskog L, Sturfelt G, Truedsson L, Alarcón-Segovia D, Gyllensten U B
Abstract excerpt
OBJECTIVE: To study the contribution of the IL10 gene to the susceptibility to systemic lupus erythematosus (SLE). METHODS: Analysis by fluorescent-semiautomated genotyping of a dinucleotide repeat located in the promoter region of the IL10 locus (microsatellite G). RESULTS: No significant difference was found in the frequencies of the microsatellite alleles of 330 Mexican patients with SLE compared to 368...
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