Article
Mucosal delivery of vaccines.
Methods (San Diego, Calif.) - 1 Sept 1999
Del Giudice G, Pizza M, Rappuoli R
Abstract excerpt
Oral delivery represents one of the most pursued approaches for large-scale human vaccination. Due to the different characteristics of mucosal immune response, as compared with systemic response, oral immunization requires particular methods of antigen preparation and selective strategies of adjuvanticity. In this paper, we describe the preparation and use of genetically detoxified bacterial toxins as mucosal...
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