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Article

Challenges and opportunities in the development of mucosal mRNA vaccines

28 Sept 2023

Abstract excerpt

mRNA vaccines have played a critical role in controlling the SARS-CoV-2 pandemic, and are being actively studied for use in other diseases. There is a growing interest in applying mRNA vaccines at mucosal surfaces as it enables access to a unique immune reservoir in a less-invasive manner. However, mucosal surfaces present several barriers to mRNA uptake, including degrading enzymes, mucus, and clearance...

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Share to Immunotherapy and Immune Responses
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PMID: 37776698
DOI: 10.1016/j.coi.2023.102388

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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