Article
[Molecular basis of hereditary hemochromatosis].
Postepy higieny i medycyny doswiadczalnej (Online) - 1 Jan 2006
Romanowski Tomasz, Sikorska Katarzyna, Bielawski Krzysztof Piotr
Abstract excerpt
Hereditary hemochromatosis (HH) is a genetic metabolic disease characterized by increased intestinal iron absorption and progressive iron loading in the cells of various organs. Human body iron homeostasis involves a number of complicated processes, some of which are not identified yet. Genetic analysis of patients affected by HH recently led to the discovery of many novel proteins and mechanisms that can...
Topics
- Animals
- Antimicrobial Cationic Peptides
- Cation Transport Proteins
- Hemochromatosis
- Hemochromatosis Protein
- Hepcidins
- Histocompatibility Antigens Class I
- Humans
- Iron
- Membrane Proteins
- Mutation
- Receptors, Transferrin
- Ferroportin