Article
[The hemochromatosis gene (HFE). Molecular analysis--diagnostic applications].
Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine - 1 Aug 1998
Ferec C, Raguenes O, Mercier A Y, Le Faou T, Chanu B, Le Poupon A M, Mercier B, Mura C
Abstract excerpt
Hemochromatosis is the most common single gene disorder in Caucasian populations. Regulation of iron balance by intestine is impaired, leading to a widespread deposition of iron, and the disease is associated with an increased risk of hepatocellular carcinoma. Typically the excess of iron treated...
Topics
- Amino Acid Substitution
- Female
- Ferritins
- Genetic Testing
- Genotype
- HLA Antigens
- Hemochromatosis
- Hemochromatosis Protein
- Histocompatibility Antigens Class I
- Humans
- Iron
- Male
- Membrane Proteins
- Phenotype
- Point Mutation
- Transferrin