Article
Haemochromatosis.
Clinical and laboratory haematology - 1 Apr 1998
Worwood M
Abstract excerpt
Genetic haemochromatosis (GH) is the most common, autosomal recessive disorder in Northern Europe. The studies which led to the identification of the HFE gene are described. In the UK over 90% of patients with GH are homozygous for the C282Y mutation of this gene. This mutation is confined to pop...
Topics
- Alleles
- Chromosomes, Human, Pair 6
- Disease Susceptibility
- Ethnicity
- Europe
- Female
- Ferritins
- Gene Frequency
- Genes, Recessive
- Genetic Linkage
- Genetic Testing
- Global Health
- HLA-A3 Antigen