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Article

Pituitary hormones as neurotrophic signals: update on hypothalamic differentiation in genetic models of altered feedback.

Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) - 1 Oct 1999

Phelps C J, Hurley D L

Abstract excerpt

Studies of mutant mice that are growth hormone (GH)- and prolactin (PRL)-deficient have provided evidence that these pituitary hormones have trophic, as well as dynamic, feedback effects on the hypothalamic neurons that regulate GH and PRL secretion (1). This review examines further evidence, from those animals and from recent transgenic models, for GH and PRL effects on neuronal differentiation. Characterization...

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Source

Identifiers

PMID: 10510245
DOI: 10.1111/j.1525-1373.1999.09994.x

Genes

PRL
GHRH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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