Article
Fv2 encodes a truncated form of the Stk receptor tyrosine kinase.
Nature genetics - 1 Oct 1999
Persons D A, Paulson R F, Loyd M R, Herley M T, Bodner S M, Bernstein A, Correll P H, Ney P A
Abstract excerpt
The Friend virus susceptibility 2 (Fv2) locus encodes a dominant host factor that confers susceptibility to Friend virus-induced erythroleukaemia in mice. We mapped Fv2 to a 1.0-Mb interval that also contained the gene (Ron) encoding the stem cell kinase receptor (Stk). A truncated form of Stk (Sf-stk), which was the most abundant form of Stk in Fv2-sensitive (Fv2ss) erythroid cells, was not expressed in Fv2...
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