Association of the A-204C polymorphism in the cholesterol 7alpha-hydroxylase gene with variations in plasma low density lipoprotein cholesterol levels in the Framingham Offspring Study.

Abstract excerpt

The first reaction of the catabolic pathway of cholesterol is catalyzed by CYP7 and serves as the rate-limiting step and major site of regulation of bile acid synthesis in the liver. A common A to C substitution at position -204 of the promoter of CYP7 gene has been associated with variations in...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cholesterol 7-alpha-Hydroxylase
• Share to Cholesterol, HDL
• Share to Cholesterol, LDL