Article
[Association of 7alpha-hydroxylase gene polymorphism with levels of plasma lipids].
Yi chuan = Hereditas - 1 May 2004
Zhou Bin, Zhang Si-Zhong, Xiao Cui-Ying, Zhang Ke-Lan, Zhang Li, Li Gui-Xing, Li Ping, Liu He-Kun, Zheng Ke-Qin
Abstract excerpt
To study the distribution of Eco31I restriction polymorphism in nucleotide -204 of 7alpha-hydroxylase gene(CYP7A1)in Sichuan Han population of China and association of the polymorphism with coronary heart disease(CHD),CYP7A1 genotyping was performed by using PCR-RFLP approach in 183 CHD patients and 101 control subjects. 7alpha-hydroxylase gene allele frequencies of C,A were 0.840 and 0.160 in CHD group and 0.822...
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