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Article

Streptococcus pyogenes pharyngeal isolates with reduced susceptibility to ciprofloxacin in Spain: mechanisms of resistance and clonal diversity.

Antimicrobial agents and chemotherapy - 1 Jan 2005

Albertí Sebastián, Cortés Guadalupe, García-Rey Cesar, Rubio Carmen, Baquero Fernando, García-Rodríguez José Angel, Bouza Emilio, Aguilar Lorenzo

Abstract excerpt

A survey of emm gene sequences and an analysis of the pulsed-field electrophoretic profiles of 30 Streptococcus pyogenes isolates with reduced susceptibilities to ciprofloxacin detected the prevalence of isolates with emm type 6 and considerable genetic diversity among isolates. The mechanism of ciprofloxacin resistance in these isolates was based on point mutations in topoisomerase IV subunit C encoded by parC,...

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Identifiers

PMID: 15616324
DOI: 10.1128/AAC.49.1.418-420.2005
PMCID: PMC538864

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Source receipt: pubmed, retrieved 7 Sept 2026.

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