Article
The TFB4 subunit of yeast TFIIH is required for both nucleotide excision repair and RNA polymerase II transcription.
The Journal of biological chemistry - 8 Oct 1999
Feaver W J, Huang W, Friedberg E C
Abstract excerpt
The N-degron strategy has been used to generate a yeast strain harboring a temperature-sensitive allele of TFB4 (tfb4(td)), the gene that encodes the 37-kDa subunit of the transcription/repair factor TFIIH. The tfb4(td) strain was sensitive to UV radiation and is defective in nucleotide excision repair in vitro. The mutant strain was also found to be an inositol auxotroph due at least in part to an inability to...
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