Article
Genetic susceptibility to the connective tissue diseases.
Current opinion in rheumatology - 1 Sept 1999
McCurdy D
Abstract excerpt
Genes important in the connective tissue diseases are being recognized in two basic ways: association studies and linkage analysis. Traditionally, association studies have confirmed a genetic influence in disease pathogenesis, especially in systemic lupus erythematosus, rheumatoid arthritis, juvenile rheumatoid arthritis, and the spondyloarthropathies. One of the strongest associations is with the HLA region. As...
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