Article
Upregulation and redistribution of cadherins reveal specific glial and muscle cell phenotypes during wallerian degeneration and muscle denervation in the mouse.
Journal of neuroscience research - 15 Oct 1999
Padilla F, Marc Mège R, Sobel A, Nicolet M
Abstract excerpt
In the present work, we investigated the expression of cadherin mRNAs in the adult neuromuscular system either under normal conditions or following experimental neurotomy. Cadherin-6, a marker of Schwann cell precursors, was not expressed in the adult peripheral nerve, while M-cadherin, cadherin-11, and N-cadherin were expressed both by glial and conjunctive cells. Moreover, the three transcripts were transiently...
Topics
- Animals
- Cadherins
- DNA-Binding Proteins
- In Situ Hybridization
- Mice
- Muscle Denervation
- Muscles
- Neuroglia
- PAX3 Transcription Factor
- Paired Box Transcription Factors
- Phenotype
- RNA, Messenger
- Schwann Cells
- Sciatic Neuropathy
- Transcription Factors
- Up-Regulation
- Wallerian Degeneration