Article
Chronically denervated rat Schwann cells respond to GGF in vitro.
Glia - 1 Nov 1998
Li H, Wigley C, Hall S M
Abstract excerpt
C-erbB receptor/neuregulin signalling plays a significant role in Schwann cell function. In vivo, Schwann cells up-regulate expression of c-erbB receptors in the first month after injury, but receptor expression is down-regulated with time to levels that are not detectable immunohistochemically. The inability of chronically denervated Schwann cells to respond adequately to signals derived from regenerating axons...
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