Article
The dare gene: steroid hormone production, olfactory behavior, and neural degeneration in Drosophila.
Development (Cambridge, England) - 1 Oct 1999
Freeman M R, Dobritsa A, Gaines P, Segraves W A, Carlson J R
Abstract excerpt
Steroid hormones mediate a wide variety of developmental and physiological events in insects, yet little is known about the genetics of insect steroid hormone biosynthesis. Here we describe the Drosophila dare gene, which encodes adrenodoxin reductase (AR). In mammals, AR plays a key role in the synthesis of all steroid hormones. Null mutants of dare undergo developmental arrest during the second larval instar or...
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