Article
Steroid hormone inactivation is required during the juvenile-adult transition in Drosophila.
Developmental cell - 14 Dec 2010
Rewitz Kim F, Yamanaka Naoki, O'Connor Michael B
Abstract excerpt
Steroid hormones are systemic signaling molecules that regulate juvenile-adult transitions in both insects and mammals. In insects, pulses of the steroid hormone 20-hydroxyecdysone (20E) are generated by increased biosynthesis followed by inactivation/clearance. Although mechanisms that control 20E synthesis have received considerable recent attention, the physiological significance of 20E inactivation remains...
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