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Article

Heads or tails? Retinoic acid will decide.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Oct 1999

Maden M

Abstract excerpt

A recent study (Niederreither et al. Nat Genet 1999;21:444-448 [Ref. 1]) describes the phenotype of a gene knockout for an enzyme, retinaldehyde dehydrogenase 2 (RALDH-2), that synthesizes retinoic acid (RA) in the early embryo. The effects generated by this single enzyme mutation are remarkably similar to those previously described in vitamin A-deprivation studies and compound retinoic acid receptor knockouts,...

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Identifiers

PMID: 10497330
DOI: 10.1002/(SICI)1521-1878(199910)21:10<809::AID-BIES2>3.0.CO;2-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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