Article
Mutations affecting development of the zebrafish retina.
Development (Cambridge, England) - 1 Dec 1996
Malicki J, Neuhauss S C, Schier A F, Solnica-Krezel L, Stemple D L, Stainier D Y, Abdelilah S, Zwartkruis F, Rangini Z, Driever W
Abstract excerpt
In a large scale screen for genetic defects in zebrafish embryogenesis we identified 49 mutations affecting development of the retina. Based on analysis of living embryos as well as histological sections, we grouped the isolated mutations into six phenotypic categories. (1) Mutations in three loci result in a loss of wild-type laminar pattern of the neural retina. (2) Defects in four loci lead to an abnormal...
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