Article
Molecular characterization of a full genome Turkish hepatitis C virus 1b isolate (HCV-TR1): a predominant viral form in Turkey.
Virus genes - 1 Oct 2002
Yildiz Esra, Oztan Asli, Sar Funda, Pinarbasi Ergun, Cetin-Atalay Rengul, Akkiz Hikmet, Ozturk Mehmet
Abstract excerpt
Based on direct sequencing information from 5'UTR and NS5B regions, we identified subtype lb as a predominant hepatitis C virus genome in Turkey, which affected more than 91% of 79 patients studied. Next, the full genome sequence of a Turkish lb isolate was obtained by the cloning of polypeptide-encoding region into 7 overlapping fragments. Turkish 1b isolate, which was named HCV-TR1, comprises 9361 nucleotides,...
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