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Article

Mutants that alter the covalent structure of catalase hydroperoxidase II from Escherichia coli.

The Journal of biological chemistry - 24 Sept 1999

Maté M J, Sevinc M S, Hu B, Bujons J, Bravo J, Switala J, Ens W, Loewen P C, Fita I

Abstract excerpt

The three-dimensional structures of two HPII variants, V169C and H392Q, have been determined at resolutions of 1.8 and 2.1 A, respectively. The V169C variant contains a new type of covalent bond between the sulfur atom of Cys(169) and a carbon atom on the imidazole ring of the essential His(128). This variant enzyme has only residual catalytic activity and contains heme b. The chain of water molecules visible in...

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Identifiers

PMID: 10488114
DOI: 10.1074/jbc.274.39.27717

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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