Human Immunodeficiency Virus Type 1-Specific Cytotoxic T Lymphocyte Activity Is Inversely Correlated with HIV Type 1 Viral Load in HIV Type 1-Infected Long-Term Survivors

Abstract excerpt

HIV-1-specific cytotoxic T cell (CTL) activity has been suggested to correlate with protection from progression to AIDS. We have examined the relationship between HIV-specific CTL activity and maintenance of peripheral blood CD4+ T lymphocyte counts and control of viral load in 17 long-term survivors (LTSs) of HIV-1 infection. Longitudinal analysis indicated that the LTS cohort demonstrated a decreased rate of...

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