Article
CD34(+) acute myeloid and lymphoid leukemic blasts can be induced to differentiate into dendritic cells.
Blood - 15 Sept 1999
Cignetti A, Bryant E, Allione B, Vitale A, Foa R, Cheever M A
Abstract excerpt
CD34(+) hematopoietic stem cells from normal individuals and from patients with chronic myelogenous leukemia can be induced to differentiate into dendritic cells (DC). The aim of the current study was to determine whether acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) cells could be induced to differentiate into DC. CD34(+) AML-M2 cells with chromosome 7 monosomy were cultured in the presence...
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