Article
Glutathione S-transferase M1 genotypes and the risk of vulvar cancer: a population-based case-control study.
American journal of epidemiology - 1 Sept 1999
Chen C, Madeleine M M, Weiss N S, Daling J R
Abstract excerpt
Glutathione S-transferases (GSTs) facilitate the excretion of a variety of potential carcinogens. Some 50-60% of Caucasians are homozygous for the null allele of GSTM1, a gene responsible for the presence of one of these enzymes. The authors examined whether women with the GSTM1 null genotype are at altered risk of vulvar cancer. They obtained peripheral blood specimens from 18- to 79-year-old residents of King,...
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