Article
Mxi1 mutations in human neurofibrosarcomas.
Japanese journal of cancer research : Gann - 1 Jul 1999
Li X J, Wang D Y, Zhu Y, Guo R J, Wang X D, Lubomir K, Mukai K, Sasaki H, Yoshida H, Oka T, Machinami R, Shinmura K, Tanaka M, Sugimura H
Abstract excerpt
Mxi1 is thought to negatively regulate Myc function and may therefore be a potential tumor suppressor gene. Little effort has yet been made to find alterations involving this gene in human solid tumors. We screened 31 human gastric cancers, 7 esophageal cancers, 85 bone and soft tissue tumors of various types, including 4 neurofibrosarcomas. We also examined 29 human tumor cell lines consisting of 12 esophageal...
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